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Guadalajara vs. Club Leon prediction, odds, Liga MX picks [3/18/2026]

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Written by Ryan Leaver

Get Guadalajara vs Club Leon predictions for Liga MX Wednesday.

Guadalajara-Club Leon Predictions and Game Preview.
Guadalajara vs. Club Leon Liga MX prediction for Wednesday, March 18, 2026.

Guadalajara will face Club Leon in the Liga MX playoffs at Estadio Akron on Wednesday, beginning at 10:07 PM ET.

Based on the latest simulation results, Dimers' proven Liga MX model predicts Guadalajara as the most likely winner of the Guadalajara vs. Club Leon game.

This article offers further insights into Wednesday's matchup, including best bets and picks.

Guadalajara vs. Club Leon prediction: Who will win?

Using powerful machine learning and data, we have simulated the result of Wednesday's Liga MX matchup between Guadalajara and Club Leon 10,000 times as part of our Liga MX predictions coverage.

Our famous predictive model currently suggests a 58.7% chance of Guadalajara winning, a 19.0% chance for Club Leon, and a 22.3% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 54% chance of going over, according to our model.

 

Guadalajara vs. Club Leon odds

We have researched the best Liga MX odds in America for this game, which are listed here:

Moneyline

Guadalajara Club Leon Draw
-250 +600 +400

Total Goals

Over 2.5 Under 2.5
-178 +144

All odds are correct at the time of publication and are subject to change.

Guadalajara vs. Club Leon picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Moneyline Club Leon +600
Total Goals Under 2.5 +144

According to our Liga MX best bets, the top play to make on this game is Under 2.5 total goals.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Guadalajara vs. Club Leon: Correct score and BTTS predictions

The top three most likely final scores, according to our model, are listed below, with a 1-0 Guadalajara win being the most probable:

Final Score Probability
GUA 1-0 LEO 11%
GUA 1-1 LEO 10.6%
GUA 2-0 LEO 10.3%

When it comes to the both teams to score (BTTS) market, we project a 52.3% chance of both sides finding the net and a 47.7% chance that at least one doesn’t.

Guadalajara vs. Club Leon game-day updates and essential details

Wednesday's action between Guadalajara and Club Leon at Estadio Akron is scheduled to begin at 10:07 PM ET.

  • Who: Guadalajara vs. Club Leon
  • Date: Wednesday, March 18, 2026
  • Time: 10:07 PM ET/7:07PM PT
  • Venue: Estadio Akron

Conclusion

According to our computer model, Guadalajara has a 58.7% win probability on Wednesday, Club Leon has a 19.0% win probability, and there is a 22.3% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Guadalajara vs. Club Leon insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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