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Queretaro vs. Cruz Azul prediction, odds, Liga MX picks [4/21/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Queretaro vs Cruz Azul predictions for Liga MX Tuesday.
Queretaro will take on Cruz Azul in the Liga MX playoffs at Estadio La Corregidora on Tuesday, commencing at 9:00 PM ET.
Based on the latest simulations, Dimers' advanced Liga MX model predicts Cruz Azul as the most likely winner of the Queretaro vs. Cruz Azul game.
This article offers an expanded analysis of Tuesday's match, including best bets and picks.
Queretaro vs. Cruz Azul prediction: Who will win?
Using powerful machine learning and data, we have simulated the result of Tuesday's Liga MX game between Queretaro and Cruz Azul, forming part of our Liga MX predictions coverage.
Our independent predictive model currently indicates a 20.4% chance of Queretaro winning, a 56.6% chance for Cruz Azul, and a 23.0% chance of a draw.
Additionally, the over/under total of 2.5 goals has a 53% chance of going over, according to our model.
Queretaro vs. Cruz Azul odds
We have researched the best Liga MX odds in America for this game, which are listed here:
Moneyline
| Queretaro | Cruz Azul | Draw |
|---|---|---|
| +340 | -135 | +295 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -150 | +105 |
All odds are correct at the time of publication and are subject to change.
Queretaro vs. Cruz Azul picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Cruz Azul | -135 |
| Total Goals | Under 2.5 | +105 |
According to our Liga MX best bets, the top play to make on this game is Cruz Azul to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Queretaro vs. Cruz Azul: Correct score and BTTS predictions
The top three most likely final scores, according to our model, are listed below, with a 1-0 Cruz Azul win being the most probable:
| Final Score | Probability |
|---|---|
| QUE 0-1 CAZ | 11.2% |
| QUE 1-1 CAZ | 10.9% |
| QUE 0-2 CAZ | 10% |
When it comes to the both teams to score (BTTS) market, we project a 52.2% chance of both sides finding the net and a 47.8% chance that at least one doesn’t.
Queretaro vs. Cruz Azul game-day updates and essential details
Tuesday's matchup between Queretaro and Cruz Azul at Estadio La Corregidora is scheduled to begin at 9:00 PM ET.
- Who: Queretaro vs. Cruz Azul
- Date: Tuesday, April 21, 2026
- Time: 9:00 PM ET/6:00PM PT
- Venue: Estadio La Corregidora
Conclusion
According to our computer model, Queretaro has a 20.4% win probability on Tuesday, Cruz Azul has a 56.6% win probability, and there is a 23.0% chance that the game will end in a draw.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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