Duke vs. Illinois Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Duke vs. Illinois NCAAF game on September 12, 2026. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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Duke
Predicted score
24
:
29
Gies Memorial Stadium (Champaign, IL)
Illinois
Gies Memorial Stadium (Champaign, IL)
Pre-Game Probabilities Last Update:

Spread

Duke +6.0
Spread
  • Duke
    53.3%
    CaesarsCaesars
  • Illinois
    46.7%
    CaesarsCaesars

Duke vs. Illinois: Detailed Breakdown

Matchup Overview

  • Teams: Duke vs. Illinois
  • Date: Saturday, September 12, 2026
  • Time: 3:30 PM ET
  • Venue: Gies Memorial Stadium (Champaign, IL)

Current betting odds

  • Spread: Illinois favored at -6
  • Total (Over/Under): 54.5
  • Moneyline Odds: Duke +190, Illinois -200

Dimers' win probabilities

  • Duke: 37%
  • Illinois: 63%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Duke 24-29 Illinois.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Duke a win probability of 37%, while Illinois has a win probability of 63%.

Summary

According to our analysis, Illinois is more likely to beat Duke in CFB action at Gies Memorial Stadium (Champaign, IL) on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Duke vs. Illinois predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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