Southeast Missouri State vs. Southern Illinois Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Southeast Missouri State vs. Southern Illinois NCAAF game on September 12, 2026. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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Southeast Missouri State
Predicted score
21
:
29
Saluki Stadium
Southern Illinois
Saluki Stadium
Pre-Game Probabilities Last Update:

Spread

Southern Illinois -7.5
Spread
  • Southeast Missouri State
    48.2%
    theScore BettheScore Bet
  • Southern Illinois
    51.8%
    theScore BettheScore Bet

Southeast Missouri State vs. Southern Illinois: Detailed Breakdown

Matchup Overview

  • Teams: Southeast Missouri State vs. Southern Illinois
  • Date: Saturday, September 12, 2026
  • Time: 7:00 PM ET
  • Venue: Saluki Stadium

Current betting odds

  • Spread: Southern Illinois favored at -7.5
  • Total (Over/Under): Not Available
  • Moneyline Odds: Southeast Missouri State +240, Southern Illinois -345

Dimers' win probabilities

  • Southeast Missouri State: 24%
  • Southern Illinois: 76%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Southeast Missouri State 21-29 Southern Illinois.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Southeast Missouri State a win probability of 24%, while Southern Illinois has a win probability of 76%.

Summary

According to our analysis, Southern Illinois is more likely to beat Southeast Missouri State in CFB action at Saluki Stadium on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Southeast Missouri State vs. Southern Illinois predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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