Miami Dolphins vs. Indianapolis Colts: Experts release early Week 10 predictions [2026]

The Miami Dolphins and Indianapolis Colts will meet in Week 10 of the NFL season at Lucas Oil Stadium on Sunday, November 15, 2026, starting at 1:00 PM ET.

Initial simulations from Dimers' trusted NFL model favor the Colts as the most likely winner of this AFC showdown.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Dolphins vs. Colts predictions page.

Miami vs. Indianapolis early predictions

Leveraging trusted machine learning and analysis, we have simulated the Dolphins vs. Colts game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Dolphins 40.9%, Colts 59.1%
• Predicted final score: Dolphins 19-21 Colts
• Spread: Dolphins (+2) 48.1%, Colts (-2) 51.9%
• Total points (40.5): Over 51.8%, Under 48.2%

As of November 9, 2026, these Dolphins-Colts figures and predictions reflect the latest data and insights available.

Dolphins vs. Colts Week 10 details

Sunday's game between the Colts and Dolphins at Lucas Oil Stadium is scheduled for November 15, 2026.

• Who: Miami Dolphins vs. Indianapolis Colts
• Date: Sunday, November 15, 2026
• Time: 1:00 PM ET/10:00 AM PT
• Venue: Lucas Oil Stadium

Dolphins vs. Colts opening odds

We've researched the best betting odds across America for this Week 10 game, which are listed here:

• Spread: Dolphins +2 (-108), Colts -2 (-110)
• Moneyline: Dolphins +127, Colts -130
• Total: Over/Under 40.5 (-104/-105)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Colts, with a 59.1% win probability, will likely beat the Dolphins in Week 10 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Dolphins vs. Colts game, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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