Andrea Guerrieri vs. Alex de Minaur prediction, odds, picks for US Open 2026

Andrea Guerrieri will face Alex de Minaur in the first round of the US Open Men's Singles 2026 on Wednesday.

Dimers' advanced tennis model projects Alex de Minaur as the most likely winner in this Guerrieri vs. de Minaur prediction.

This article offers a closer look at Wednesday's match, including best bets and picks.

Guerrieri vs. de Minaur prediction and odds

Using trusted machine learning and data, we have simulated the result of Wednesday's Guerrieri-de Minaur men's singles match, forming part of our tennis predictions coverage.

Our independent predictive model currently gives de Minaur a 94% chance of defeating Guerrieri in the US Open 2026.

Latest betting odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

• Moneyline: Alex de Minaur -3333, Andrea Guerrieri +1500

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Guerrieri @ +1500 via DraftKings
• First Set: de Minaur @ -150 via DraftKings

According to our tennis best bets, the top play to make on this match is over 29.5 total games.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & first serve details

The US Open 2026 match between Andrea Guerrieri and Alex de Minaur is scheduled to begin on Wednesday at 12:40 PM ET.

• Who: Andrea Guerrieri vs. Alex de Minaur
• Date: Wednesday, September 2, 2026
• Approx. Time: 12:40 PM ET/9:40AM PT
• Tournament: US Open Men's Singles 2026
• Round: First round

All dates and times in this article are United States Eastern Time unless otherwise noted.

Conclusion

We predict Alex de Minaur, with a 94% win probability, will likely beat Andrea Guerrieri at the US Open 2026.

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