Francisco Comesana vs. Flavio Cobolli prediction, odds, picks for US Open 2026

Using trusted machine learning and data, we have simulated the result of Sunday's Comesana-Cobolli men's singles match, forming part of our tennis predictions coverage.

Our famous predictive model gives Cobolli a 78% chance of beating Comesana in the US Open 2026.

Francisco Comesana vs. Flavio Cobolli odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

• Moneyline: Flavio Cobolli -450, Francisco Comesana +350

All odds are correct at the time of publication and are subject to change.

Comesana vs. Cobolli picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Comesana @ +350 via DraftKings
• First Set: Cobolli @ -120 via DraftKings

According to our best tennis bets, the top play to make on this match is Francisco Comesana to win the first set.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Comesana vs. Cobolli updates and essential details

The US Open 2026 match between Francisco Comesana and Flavio Cobolli is scheduled to commence on Sunday at 11:00 AM ET.

• Who: Francisco Comesana vs. Flavio Cobolli
• Date: Sunday, August 30, 2026
• Approx. Time: 11:00 AM ET/8:00AM PT
• Tournament: US Open Men's Singles 2026
• Round: First round

All dates and times mentioned in this article are United States Eastern Time unless otherwise stated.

Conclusion

We predict Flavio Cobolli, with a 78% win probability, will likely beat Francisco Comesana at the US Open 2026.

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