Jan-Lennard Struff vs. Francisco Cerundolo prediction, odds, picks for US Open 2026

Jan-Lennard Struff will face Francisco Cerundolo in the second round of the US Open Men's Singles 2026 on Thursday.

Dimers' advanced tennis model projects Francisco Cerundolo as the most likely winner in this Struff vs. Cerundolo prediction.

This article offers an expanded analysis of Thursday's match, including best bets and picks.

Struff vs. Cerundolo prediction and odds

Using innovative machine learning and data analysis, we have simulated the outcome of Thursday's Struff-Cerundolo men's singles match, forming part of our tennis predictions coverage.

Our famous predictive model currently gives Cerundolo a 60% chance of defeating Struff in the US Open 2026.

Additionally, Cerundolo has a 56% chance of winning the first set. The simulations also show Struff (+3.5) has a 53% chance of covering the games spread, while the over 37.5 games has a 52% chance of hitting, according to our model.

Latest betting odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

• Moneyline: Francisco Cerundolo -156, Jan-Lennard Struff +137
• First Set: Struff +120, Cerundolo -152

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Cerundolo @ -156 via DraftKings
• First Set: Cerundolo @ -120 via DraftKings

According to our tennis best bets, the top play to make on this match is over 37.5 total games.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & first serve details

The US Open 2026 match between Jan-Lennard Struff and Francisco Cerundolo is scheduled to start on Thursday at 11:00 AM ET.

• Who: Jan-Lennard Struff vs. Francisco Cerundolo
• Date: Thursday, September 3, 2026
• Approx. Time: 11:00 AM ET/8:00AM PT
• Tournament: US Open Men's Singles 2026
• Round: Second round

All dates and times mentioned in this article are United States Eastern Time unless otherwise noted.

Conclusion

We predict Francisco Cerundolo, with a 60% win probability, will likely beat Jan-Lennard Struff at the US Open 2026.

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