Naomi Osaka vs. Anastasia Zakharova prediction, odds, picks for US Open 2026

Naomi Osaka will face Anastasia Zakharova in the first round of the US Open Women's Singles 2026 on Monday.

Dimers' proven tennis model projects Naomi Osaka as the most likely winner in this Osaka vs. Zakharova prediction.

This article offers further insights into Monday's match, including best bets and picks.

Osaka vs. Zakharova prediction: Who will win and advance to the second round?

Using trusted machine learning and data, we have simulated the outcome of Monday's Osaka-Zakharova women's singles match, forming part of our tennis predictions coverage.

Our famous predictive model gives Osaka an 86% chance of winning against Zakharova in the US Open 2026.

Naomi Osaka vs. Anastasia Zakharova odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

• Moneyline: Anastasia Zakharova +720, Naomi Osaka -990

All odds are correct at the time of publication and are subject to change.

Osaka vs. Zakharova picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Zakharova @ +720 via DraftKings
• First Set: Zakharova @ +100 via DraftKings

According to our best tennis bets, the top play to make on this match is over 19.5 total games.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Osaka vs. Zakharova updates and essential details

The US Open 2026 match between Naomi Osaka and Anastasia Zakharova is scheduled to start on Monday at 8:40 PM ET.

• Who: Naomi Osaka vs. Anastasia Zakharova
• Date: Monday, August 31, 2026
• Approx. Time: 8:40 PM ET/5:40PM PT
• Tournament: US Open Women's Singles 2026
• Round: First round

All dates and times mentioned in this article are United States Eastern Time unless otherwise noted.

Conclusion

We predict Naomi Osaka, with an 86% win probability, will likely beat Anastasia Zakharova at the US Open 2026.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.