Stefanos Tsitsipas vs. Mikhail Kukushkin prediction, odds, picks for ATP Almaty Open 2026

Stefanos Tsitsipas and Mikhail Kukushkin are scheduled to meet in the round of 16 of the ATP Almaty Open event on Wednesday.

Dimers' advanced tennis model projects Stefanos Tsitsipas as the most likely winner in this Tsitsipas vs. Kukushkin prediction.

This article offers a closer look at Wednesday's match, including best bets and picks.

Tsitsipas vs. Kukushkin prediction and odds

Using powerful machine learning and data analysis, we have re-simulated the outcome of Wednesday's Tsitsipas-Kukushkin men's singles match, forming part of our tennis predictions coverage.

Our famous predictive model currently gives Tsitsipas a 90% chance of beating Kukushkin at the ATP Almaty Open tournament. Additionally, Tsitsipas has an 84% chance of winning the first set. The simulations also show Kukushkin (+5.5) has a 53% chance of covering the games spread, while the under 19.5 games has a 54% chance of hitting, according to our model.

Latest betting odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

• Moneyline: Mikhail Kukushkin +1000, Stefanos Tsitsipas -1429
• First Set: Tsitsipas -714, Kukushkin +450

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Kukushkin @ +1000 via DraftKings
• First Set: Kukushkin @ -105 via DraftKings

According to our best tennis bets, the top play to make on this match is Mikhail Kukushkin to win the first set.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & first serve details

The ATP Almaty Open match between Stefanos Tsitsipas and Mikhail Kukushkin is scheduled to start on Wednesday at 10:30 AM ET.

• Who: Stefanos Tsitsipas vs. Mikhail Kukushkin
• Date: Wednesday, October 21, 2026
• Approx. Time: 10:30 AM ET/7:30 AM PT
• Tournament: ATP Almaty, Kazakhstan Men's Singles 2026
• Round: Round of 16

All dates and times mentioned in this article are United States Eastern Time unless otherwise stated.

Conclusion

We predict Stefanos Tsitsipas, with a 90% win probability, will likely beat Mikhail Kukushkin at the ATP Almaty Open tournament.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary Tennis prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.