Charleston Southern vs. South Florida prediction, odds, pick for Nov. 2, 2026

South Florida is favored to beat Charleston Southern at Yuengling Center on Monday (7:00 PM ET), according to Dimers' men's college basketball model.

Our Charleston Southern vs. South Florida prediction gives South Florida a 96.4% chance of winning, and the latest odds suggest there's betting value on South Florida to cover at -21.5, too.

Charleston Southern vs. South Florida key predictions

• Predicted score: South Florida 91-68 Charleston Southern
• South Florida win probability: 96.4%
• Charleston Southern win probability: 3.6%
• South Florida -21.5 spread: 52.0% cover probability
• Over 158.5 points: 51.4% probability

Our men's college basketball predictions project each team's final score using offensive and defensive efficiency, recent performance, long-term trends, and matchup-specific factors.

We calculate win, spread, and total probabilities based on these projections and historical CBB scoring patterns, then compare them with the latest odds to find betting value.

Charleston Southern vs. South Florida odds

Here are the best available odds across the moneyline, spread, and total points markets we track.

• Charleston Southern moneyline: +2000 (DraftKings)
• South Florida moneyline: -6502 (DraftKings)
• Charleston Southern +21.5: -108 (DraftKings)
• South Florida -21.5: -108 (BetRivers)
• Over 158.5 points: -110 (Caesars Sportsbook)
• Under 158.5 points: -110 (Caesars Sportsbook)

Odds are subject to change and may vary by location.

Charleston Southern vs. South Florida pick: South Florida -21.5 (-108)

Our model makes South Florida the likelier winner, and our best value bet is South Florida to cover the -21.5 spread at -108 on BetRivers, too.

Those odds give South Florida an implied cover probability of 51.9%, while our model puts it at 52.0%.

That's a 0.1% edge, the largest across the moneyline, spread, and total points markets for this game.

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Charleston Southern vs. South Florida game details

• Matchup: Charleston Southern Buccaneers vs. South Florida Bulls
• Date: Monday, November 2, 2026
• Time: 7:00 PM ET
• Venue: Yuengling Center

About this prediction

This preview uses predictions from our men's college basketball models, presented through a template written by our editorial team. Matchup details fill in automatically.

Predictions are estimates, not guarantees, and can change as new information comes in, such as injury news or lineup changes. Learn how our predictions work.

Dimers encourages responsible gambling.