College basketball championship predictions and odds: Duke, Florida lead

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Written by Nick Slade
Reviewed by Dave Garofolo

Dimers’ model gives the Blue Devils a slim edge over the preseason No. 1 Gators as both try to shake off tournament letdowns the past two years.

Michigan Wolverines are the defending champions.
Michigan is rated just a 1.6% chance (+4000 odds) to go back-to-back in 2027, with Duke and Florida the top picks to win the National Championship.

Duke and Florida enter the 2026-27 college basketball season as the two clear favorites to win it all, and Dimers’ latest numbers have them separated by less than two points of win probability. Duke sits at 10.9% to win the national championship at best odds of +600, with Florida just behind at 9.1% and +650. No other team in Dimers’ top 10, including UConn at 5.1%, is within shouting distance of the top two.

The pairing is familiar. Duke and Florida have been the two most talked-about national title contenders for two straight preseasons now, and both have come up short when it mattered most. The season opens Sunday, and the first meaningful test for either team comes fast: Florida hosts Duke on Dec. 1 in the SEC/ACC Challenge.

Check Dimers’ college basketball predictions for how the model sees that game and every other matchup on the slate.

Where the numbers stand

Dimers’ top 10 for the national championship also includes Illinois (4.7%, +1400), Arizona (3.6%, +2000), Michigan State (3.4%, +2000), Texas (3.3%, +2200), Louisville (2.8%, +2500), Arkansas (2.6%, +2500) and Houston (2.5%, +3000).

The gap between the model and the human polls is worth noting. The AP preseason Top 25 has Florida at No. 1, the first time the Gators have opened a season there since 2006, with 47 of 59 first-place votes. Duke is No. 2 with 10 first-place votes. Dimers’ title odds flip that order slightly, giving Duke a small edge in actual championship probability even though Florida carries the higher public ranking. Full odds and lines for every team in the field are available on Dimers’ college basketball futures page.


Duke is chasing a different ending

Duke has been here before, and recently. In 2025, the Blue Devils were favored entering the Final Four with Cooper Flagg leading the way, only to lose 70-67 to Houston in a classic. Last season, with freshman Cameron Boozer carrying a loaded roster, Duke blew a 19-point lead in the Elite Eight and fell 73-72 to UConn, missing the Final Four for a second straight year.

Boozer has since left for the NBA. Jon Scheyer’s fifth Duke team is built around transfer guard John Blackwell and center Patrick Ngongba II, both preseason All-ACC First Team picks, plus returning sophomore Cayden Boozer and five-star freshman Joaquim Boumtje Boumtje, the preseason favorite for ACC Rookie of the Year. Duke was picked to win the ACC regular-season title in the media poll with 45 of a possible first-place votes, and the program’s non-conference schedule, including the Dec. 1 trip to Florida, was built to test it early. Dimers’ player projections track how that new core is performing as the season unfolds.

Florida is betting on continuity

Florida’s letdown came even earlier. The Gators won the program’s third national title in April 2025, then entered last season as a repeat No. 1 seed, only to get knocked out by Iowa in the second round, the earliest tournament exit of Todd Golden’s tenure as a top seed.

The response was to keep the group together rather than rebuild it. Rueben Chinyelu, Alex Condon and Thomas Haugh all turned down the NBA draft to return, and Florida brings back four starters and nine of its top 11 scorers from a 27-8 team. Chinyelu averaged a double-double (10.9 points, 11.2 rebounds), the first Florida player to do that in 50 years. Haugh led the team at 17.1 points per game, and Boogie Fland is back running the offense. Golden, who fielded NBA interest of his own last spring, signed a third contract extension in three years in August.

Florida opens Monday against No. 14 Miami in Tampa before a schedule that includes Houston and Kansas in Las Vegas and an SEC opener at No. 7 Texas on Jan. 2.

Dimers Pro subscribers get the full slate of predictions and best bets as both teams work through that schedule, not just the top-line national championship numbers. Explore Dimers Pro for complete coverage of Duke, Florida and every other contender all season, with the option to cancel or pause anytime.

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To give you the most accurate and helpful information, this article has been reviewed and edited by Dave Garofolo through our fact-checking process.
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Written by
Nick Slade
Chief Content Officer

Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.

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