College football picks today: Week 8 Thursday best bets include Liberty vs. Kennesaw State play [10/22/2026]
Get college football picks and best bets for Thursday, October 22, 2026.

Today’s college football picks for October 22, 2026 are here, with Liberty vs. Kennesaw State and James Madison vs. Appalachian State among the top plays identified by our model across Thursday’s college football action.
Dimers’ predictive analytics engine runs 24/7, searching the latest football odds to uncover legitimate betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of college football picks tonight [10/22, updated 4:38AM ET]
Below, you’ll find today’s college football best bets, ranked by edge for Thursday, October 22, 2026.
Kennesaw State +8.5 (+108)
- Edge: 3.9%
- Probability: 51.9%
- Matchup: Liberty vs. Kennesaw State (7:00PM ET)
Our model has identified value on Kennesaw State +8.5 at 48¢ odds. A 51.9% probability produces an edge of 3.9%, making this the strongest play for today's college football slate.
Appalachian State +11.5 (-104)
- Edge: 3.1%
- Probability: 54.1%
- Matchup: James Madison vs. Appalachian State (7:00PM ET)
Appalachian State +11.5 carries a 3.1% edge and a probability of 54.1% at 51¢ odds, according to our model.
Memphis ML (78¢)
- Edge: 2.2%
- Probability: 80.2%
- Matchup: East Carolina vs. Memphis (7:30PM ET)
Memphis ML at 78¢ odds shows a 2.2% edge, supported by a 80.2% probability in simulations.
Kennesaw State ML (+344)
- Edge: 2.2%
- Probability: 24.7%
- Matchup: Liberty vs. Kennesaw State (7:00PM ET)
A 2.2% edge and 24.7% probability makes Kennesaw State at the moneyline a value play in the Liberty vs. Kennesaw State matchup, per our model.
NCAAF best bets summary: Thursday, 10/22/2026
As of 4:38AM ET, here are our top college football bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Prob. |
|---|---|---|---|---|
| Liberty vs. Kennesaw State | Kennesaw State +8.5 | 48¢ @ Novig | 3.9% | 51.9% |
| James Madison vs. Appalachian State | Appalachian State +11.5 | 51¢ @ Novig | 3.1% | 54.1% |
| East Carolina vs. Memphis | Memphis ML | 78¢ @ Novig | 2.2% | 80.2% |
| Liberty vs. Kennesaw State | Kennesaw State ML | 23¢ @ Novig | 2.2% | 24.7% |
List of upcoming college football games to bet on now
- Liberty vs. Kennesaw State (7:00PM ET, Thursday)
- James Madison vs. Appalachian State (7:00PM ET, Thursday)
- East Carolina vs. Memphis (7:30PM ET, Thursday)
College football offer for Week 8
Make the most of the picks in this article, including Kennesaw State +8.5, with the Bet365 Sportsbook offer below:
Conclusion
Our college football best bets are locked and loaded for October 22, 2026, featuring plays such as Kennesaw State +8.5 vs. Liberty and Appalachian State +11.5. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.



