College football picks today: Week 8 Thursday best bets include Liberty vs. Kennesaw State play [10/22/2026]

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Written by Ryan Leaver

Get college football picks and best bets for Thursday, October 22, 2026.

College Football Best Bets.
These college football betting picks for October 22, 2026, are based on the latest odds and probabilities for Thursday's games.

Today’s college football picks for October 22, 2026 are here, with Liberty vs. Kennesaw State and James Madison vs. Appalachian State among the top plays identified by our model across Thursday’s college football action.

Dimers’ predictive analytics engine runs 24/7, searching the latest football odds to uncover legitimate betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of college football picks tonight [10/22, updated 4:38AM ET]

Below, you’ll find today’s college football best bets, ranked by edge for Thursday, October 22, 2026.

Kennesaw State +8.5 (+108)

Our model has identified value on Kennesaw State +8.5 at 48¢ odds. A 51.9% probability produces an edge of 3.9%, making this the strongest play for today's college football slate.

 

Appalachian State +11.5 (-104)

Appalachian State +11.5 carries a 3.1% edge and a probability of 54.1% at 51¢ odds, according to our model.

 

Memphis ML (78¢)

Memphis ML at 78¢ odds shows a 2.2% edge, supported by a 80.2% probability in simulations.

 

Kennesaw State ML (+344)

A 2.2% edge and 24.7% probability makes Kennesaw State at the moneyline a value play in the Liberty vs. Kennesaw State matchup, per our model.

 

NCAAF best bets summary: Thursday, 10/22/2026

As of 4:38AM ET, here are our top college football bets by edge recommended by our model:

Matchup Bet Odds Edge Prob.
Liberty vs. Kennesaw State Kennesaw State +8.5 48¢ @ Novig 3.9% 51.9%
James Madison vs. Appalachian State Appalachian State +11.5 51¢ @ Novig 3.1% 54.1%
East Carolina vs. Memphis Memphis ML 78¢ @ Novig 2.2% 80.2%
Liberty vs. Kennesaw State Kennesaw State ML 23¢ @ Novig 2.2% 24.7%
 

List of upcoming college football games to bet on now

College football offer for Week 8

Make the most of the picks in this article, including Kennesaw State +8.5, with the Bet365 Sportsbook offer below:


Conclusion

Our college football best bets are locked and loaded for October 22, 2026, featuring plays such as Kennesaw State +8.5 vs. Liberty and Appalachian State +11.5. Powered by advanced simulations, these picks are here to boost your betting game.

Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.

All odds and probabilities in this article are correct and accurate at the time of publication.

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Written by
Ryan Leaver
Senior Editor

Ryan Leaver specializes in sports betting analysis across the NBA, NFL, college football, college basketball, and soccer. Drawing on advanced statistical models, simulations, and historical data, he produces game previews, betting picks, player prop analysis, and futures coverage to help bettors make more informed decisions.

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