Delaware State vs. USF prediction favors South Florida to win in college football Week 3 [2026]

South Florida will square off with Delaware State in Week 3 college football action at Raymond James Stadium on Saturday, with kickoff at 7:00 PM ET.

Dimers' proven college football model projects South Florida as the most likely winner in this Delaware State vs. USF prediction.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Delaware State vs. USF prediction and odds

Using innovative machine learning and statistical analysis, we have re-simulated the outcome of Delaware State vs. USF, forming part of our college football predictions coverage.

Our independent predictive model gives South Florida a 99.1% chance of beating Delaware State. Our predicted final score has South Florida winning 47-11. According to our model, Delaware State (+36.5) has a 52.8% chance of covering the spread, while the 60.5-point over/under has a 52.7% chance of staying under.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Delaware State +36.5 (-105) / USF -36.5 (-112)
• Moneyline: Delaware State , USF

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Under @ -110 via DraftKings

According to our best college football bets, the top play to make on this game is Delaware State +36.5.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between USF and Delaware State at Raymond James Stadium is scheduled to begin at 7:00 PM ET.

• Who: Delaware State vs. South Florida
• Date: Saturday, September 19, 2026
• Time: 7:00 PM ET/4:00PM PT
• Venue: Raymond James Stadium

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Conclusion

We predict South Florida, with a 99.1% win probability, will likely beat Delaware State in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.