Eastern Washington vs. South Dakota prediction favors South Dakota to win in college football Week 2 [2026]

South Dakota will face Eastern Washington in Week 2 college football action at The DakotaDome on Saturday, starting at 2:00 PM ET.

Dimers' proven college football model projects South Dakota as the most likely winner in this Eastern Washington vs. South Dakota prediction.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons.

Eastern Washington vs. South Dakota prediction and odds

Using trusted machine learning and data, we have re-simulated the result of Eastern Washington vs. South Dakota, forming part of our college football predictions coverage.

Our independent predictive model currently gives South Dakota an 88.2% chance of beating Eastern Washington. Our predicted final score has South Dakota winning 38-22. According to our model, South Dakota (-15.5) has a 52.3% chance of covering the spread, while the 62-point over/under has a 53.5% chance of staying under.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Eastern Washington +15.5 (-108) / South Dakota -15.5 (-110)
• Moneyline: Eastern Washington +500, South Dakota -700
• Total: Over/Under 62 (-113/-109)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: South Dakota -15.5 @ -110 via bet365
• Moneyline: South Dakota @ -700 via bet365
• Total: Under 62 @ -109 via Caesars

According to our college football best bets, the top play to make on this game is Under 62 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between South Dakota and Eastern Washington at The DakotaDome is scheduled to begin at 2:00 PM ET.

• Who: Eastern Washington vs. South Dakota
• Date: Saturday, September 12, 2026
• Time: 2:00 PM ET/11:00AM PT
• Venue: The DakotaDome

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Conclusion

We predict South Dakota, with an 88.2% win probability, will likely beat Eastern Washington in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.