Holy Cross vs. Harvard prediction favors Harvard to win in college football Week 7 [2026]

Harvard will square off with Holy Cross in Week 7 college football action at Harvard Stadium on Saturday, beginning at 1:00 PM ET.

Dimers' proven college football model projects Harvard as the most likely winner in this Holy Cross vs. Harvard prediction.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Holy Cross vs. Harvard prediction and odds

Using trusted machine learning and data analysis, we have re-simulated the outcome of Holy Cross vs. Harvard, forming part of our college football predictions coverage.

Our leading predictive model currently gives Harvard an 88.9% chance of defeating Holy Cross. Our predicted final score has Harvard winning 31-15. According to our model, Harvard (-15.5) has a 52.0% chance of covering the spread, while the 45.5-point over/under has a 54.3% chance of going over.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Holy Cross +15.5 (-110) / Harvard -15.5 (-110)
• Moneyline: Holy Cross +545, Harvard -567
• Total: Over/Under 45.5 (-104/-115)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Harvard -15.5 @ -110 via bet365
• Moneyline: Harvard @ 85¢ via Novig
• Total: Over 45.5 @ -104 via DraftKings

According to our college football best bets, the top play to make on this game is Harvard to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Harvard and Holy Cross at Harvard Stadium is scheduled to start at 1:00 PM ET.

• Who: Holy Cross vs. Harvard
• Date: Saturday, October 17, 2026
• Time: 1:00 PM ET/10:00AM PT
• Venue: Harvard Stadium

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Conclusion

We predict Harvard, with an 88.9% win probability, will likely beat Holy Cross in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.