Indiana vs. Michigan prediction: Why Indiana is favored to win in college football Week 8 [2026]

Michigan and Indiana will lock horns in Week 8 college football action at Michigan Stadium on Saturday, beginning at 12:00 PM ET.

Dimers' proven college football model projects Indiana as the most likely winner in this Indiana vs. Michigan prediction.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Indiana vs. Michigan prediction and odds

Using trusted machine learning and data, we have re-simulated the outcome of Indiana vs. Michigan, forming part of our college football predictions coverage.

Our famous predictive model currently gives Indiana a 70.3% chance of beating Michigan. Our predicted final score has Indiana winning 25-19. According to our model, Michigan (+9.5) has a 56.2% chance of covering the spread, while the 44.5-point over/under has a 50.3% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Indiana -9.5 (+120) / Michigan +9.5 (-122)
• Moneyline: Indiana -270, Michigan +260
• Total: Over/Under 44.5 (+115/-117)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Michigan +9.5 @ 55¢ via Novig
• Moneyline: Michigan @ +260 via BetRivers
• Total: Over 44.5 @ 46¢ via Novig

According to our college football best bets, the top play to make on this game is Over 44.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between Michigan and Indiana at Michigan Stadium is scheduled to start at 12:00 PM ET.

• Who: Indiana vs. Michigan
• Date: Saturday, October 24, 2026
• Time: 12:00 PM ET/9:00 AM PT
• Venue: Michigan Stadium

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Conclusion

We predict Indiana, with a 70.3% win probability, will likely beat Michigan in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.