William & Mary vs. Lehigh prediction favors Lehigh to win in college football Week 2 [2026]

Lehigh will square off with William & Mary in Week 2 college football action at Murray H. Goodman Stadium on Saturday, beginning at 2:00 PM ET.

Dimers' proven college football model projects Lehigh as the most likely winner in this William & Mary vs. Lehigh prediction.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons.

William & Mary vs. Lehigh prediction and odds

Using trusted machine learning and data, we have re-simulated the result of William & Mary vs. Lehigh, forming part of our college football predictions coverage.

Our independent predictive model currently gives Lehigh an 81.4% chance of defeating William & Mary. Our predicted final score has Lehigh winning 31-17. According to our model, Lehigh (-13.5) has a 53.5% chance of covering the spread, while the 47.5-point over/under has a 54.3% chance of going over.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: William & Mary +13.5 (-110) / Lehigh -13.5 (-112)
• Moneyline: William & Mary +325, Lehigh -400
• Total: Over/Under 47.5 (-110/-108)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Lehigh -13.5 @ -112 via DraftKings
• Moneyline: Lehigh @ -400 via bet365
• Total: Over 47.5 @ -110 via bet365

According to our college football best bets, the top play to make on this game is Over 47.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Lehigh and William & Mary at Murray H. Goodman Stadium is scheduled to commence at 2:00 PM ET.

• Who: William & Mary vs. Lehigh
• Date: Saturday, September 12, 2026
• Time: 2:00 PM ET/11:00AM PT
• Venue: Murray H. Goodman Stadium

College football Week 2 promos

Make the most of Dimers' William & Mary vs. Lehigh predictions by exploring the Bet365 Sportsbook offer below:

Conclusion

We predict Lehigh, with an 81.4% win probability, will likely beat William & Mary in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.