Youngstown State vs. Indiana State prediction: Why Youngstown State is favored to win in college football Week 6 [2026]

Indiana State and Youngstown State will lock horns in Week 6 college football action at Memorial Stadium on Saturday, beginning at 1:00 PM ET.

Dimers' advanced college football model projects Youngstown State as the most likely winner in this Youngstown State vs. Indiana State prediction.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Youngstown State vs. Indiana State prediction and odds

Using innovative machine learning and statistical analysis, we have re-simulated the outcome of Youngstown State vs. Indiana State, forming part of our college football predictions coverage.

Our famous predictive model currently gives Youngstown State a 92.6% chance of defeating Indiana State. Our predicted final score has Youngstown State winning 40-22. According to our model, Indiana State (+19.5) has a 51.6% chance of covering the spread, while the 64.5-point over/under has a 53.1% chance of staying under.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Youngstown State -19.5 (-113) / Indiana State +19.5 (-109)
• Moneyline: Youngstown State -1600, Indiana State +800
• Total: Over/Under 64.5 (-110/-112)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Indiana State +19.5 @ -109 via Caesars
• Moneyline: Youngstown State @ -1600 via bet365
• Total: Under 64.5 @ -112 via Caesars

According to our college football best bets, the top play to make on this game is Under 64.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Indiana State and Youngstown State at Memorial Stadium is scheduled to commence at 1:00 PM ET.

• Who: Youngstown State vs. Indiana State
• Date: Saturday, October 10, 2026
• Time: 1:00 PM ET/10:00AM PT
• Venue: Memorial Stadium

College football Week 6 promos

Make the most of Dimers' Youngstown State vs. Indiana State predictions by exploring the Bet365 Sportsbook offer below:

In Texas or Oklahoma? Check out this exclusive offer where you can secure $25 in Predictions Dollars as soon as either team scores in today's Sooners-Longhorns clash.

Conclusion

We predict Youngstown State, with a 92.6% win probability, will likely beat Indiana State in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.