Louisiana-Lafayette vs. Southern California Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Louisiana-Lafayette vs. Southern California NCAAF game on September 12, 2026. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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Louisiana-Lafayette
Predicted score
13
:
44
Los Angeles Memorial Coliseum
Southern California
Los Angeles Memorial Coliseum
Pre-Game Probabilities Last Update:

Spread

Louisiana-Lafayette +31.5
Spread
  • Louisiana-Lafayette
    54.3%
    bet365bet365
  • Southern California
    45.7%
    bet365bet365

Louisiana-Lafayette vs. Southern California: Detailed Breakdown

Matchup Overview

  • Teams: Louisiana-Lafayette vs. Southern California
  • Date: Saturday, September 12, 2026
  • Time: 11:00 PM ET
  • Venue: Los Angeles Memorial Coliseum

Current betting odds

  • Spread: Southern California favored at -31.5
  • Total (Over/Under): 60.5
  • Moneyline Odds: Louisiana-Lafayette +3500, Southern California -10000

Dimers' win probabilities

  • Louisiana-Lafayette: 3%
  • Southern California: 97%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Louisiana-Lafayette 13-44 Southern California.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Louisiana-Lafayette a win probability of 3%, while Southern California has a win probability of 97%.

Summary

According to our analysis, Southern California is more likely to beat Louisiana-Lafayette in CFB action at Los Angeles Memorial Coliseum on Sunday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Louisiana-Lafayette vs. Southern California predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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