MLB picks today: Sunday's MLB best bets include Athletics vs. Guardians play [9/20/2026]

Athletics vs. Guardians Over 7.5 runs (+111)

• Edge: 7.5%
• Probability: 54.9%
• Matchup: Athletics vs. Guardians (1:40PM ET)

Our model has identified value on Over 7.5 runs in Athletics vs. Guardians at 47¢ odds. A 54.9% probability produces an edge of 7.5%, making this the strongest play for today's MLB slate.

Brewers vs. Orioles Over 7.5 runs (-108)

• Edge: 6.1%
• Probability: 58%
• Matchup: Brewers vs. Orioles (7:20PM ET)

Brewers vs. Orioles over 7.5 runs carries a 6.1% edge and a probability of 58% at 52¢ odds, according to our model.

Braves vs. Astros Over 8.5 runs (+111)

• Edge: 6.0%
• Probability: 53.4%
• Matchup: Braves vs. Astros (2:10PM ET)

Braves vs. Astros Over 8.5 runs at 47¢ odds shows a 6.0% edge, supported by a 53.4% probability in simulations.

Athletics ML (+217)

• Edge: 5.7%
• Probability: 37.2%
• Matchup: Athletics vs. Guardians (1:40PM ET)

A 5.7% edge and 37.2% probability makes Athletics at the moneyline a value play in the Athletics vs. Guardians matchup, per our model.

Yankees vs. Diamondbacks Over 8.5 runs (+104)

• Edge: 5.6%
• Probability: 54.7%
• Matchup: Yankees vs. Diamondbacks (4:10PM ET)

Yankees vs. Diamondbacks Over 8.5 runs at 49¢ presents a 5.6% edge, with simulations resulting in a probability of 54.7%.

Orioles ML (+186)

• Edge: 5.0%
• Probability: 39.9%
• Matchup: Brewers vs. Orioles (7:20PM ET)

Our model finds value on Orioles to win at 35¢, supported by an edge of 5.0%.

Mets ML (+153)

• Edge: 4.4%
• Probability: 43.9%
• Matchup: Phillies vs. Mets (1:10PM ET)

Our model has uncovered value on Phillies-Mets to finish as a tie after 90 minutes at 40¢. A 43.9% probability produces a 4.4% edge, making this a strong play for today's MLB action.

Mariners vs. Rockies Over 10.5 runs (-113)

• Edge: 3.9%
• Probability: 57%
• Matchup: Mariners vs. Rockies (3:10PM ET)

A 3.9% edge on a 57% probability makes Over 10.5 runs at 53¢a solid value play in today's Mariners vs. Rockies matchup.

Marlins vs. PadresOver 8.5 runs (+117)

• Edge: 3.8%
• Probability: 49.9%
• Matchup: Marlins vs. Padres (4:10PM ET)

Our model projects value on Over 8.5 runs at 46¢. A 49.9% probability produces a 3.8% edge, making the Over the favorable side in today's matchup.

Mets +1.5 (-113)

• Edge: 3.8%
• Probability: 56.8%
• Matchup: Phillies vs. Mets (1:10PM ET)

Rounding out our top 10 bets, Mets +1.5 at 53¢ shows a 56.8% probability and a 3.8% edge.

MLB best bets summary: Sunday, 9/20/2026

As of 5:16AM ET, here are our top MLB bets by edge recommended by our model:

List of upcoming MLB games to bet on [9/20/2026]

• Phillies vs. Mets (1:10PM ET, Sunday)
• Royals vs. Pirates (1:35PM ET, Sunday)
• Athletics vs. Guardians (1:40PM ET, Sunday)
• Red Sox vs. Rays (1:40PM ET, Sunday)
• Cubs vs. Reds (1:40PM ET, Sunday)
• Tigers vs. White Sox (2:10PM ET, Sunday)
• Braves vs. Astros (2:10PM ET, Sunday)
• Nationals vs. Cardinals (2:15PM ET, Sunday)
• Blue Jays vs. Rangers (2:35PM ET, Sunday)
• Mariners vs. Rockies (3:10PM ET, Sunday)
• Twins vs. Angels (4:07PM ET, Sunday)
• Marlins vs. Padres (4:10PM ET, Sunday)
• Yankees vs. D-Backs (4:10PM ET, Sunday)
• Brewers vs. Orioles (7:20PM ET, Sunday)

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Conclusion

Our MLB best bets are locked and loaded for September 20, 2026, featuring plays such as over 7.5 runs in the Athletics vs. Guardians matchup and over 7.5 runs in the Brewers vs. Orioles matchup. Powered by advanced simulations, these picks are here to boost your betting game.

Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.

All odds and probabilities in this article are correct and accurate at the time of publication.