Nashville SC vs. Chicago Fire prediction, odds, MLS picks [9/19/2026]

Nashville will square off with Chicago in MLS action at Geodis Park on Saturday, beginning at 9:30 PM ET.

Dimers' advanced MLS model projects Nashville as the most likely winner in this Nashville vs. Chicago prediction.

This article offers further insights into Saturday's match, including best bets and picks.

Nashville SC vs. Chicago Fire prediction and odds

Using trusted machine learning and statistical analysis, we have re-simulated the outcome of Saturday's MLS matchup between Nashville and Chicago, forming part of our MLS predictions coverage.

Our famous predictive model indicates a 59.0% chance of Nashville winning, a 20.1% chance for Chicago, and a 20.9% chance of a draw. Additionally, the 2.5-goal over/under has a 61.7% chance of going over., according to our model.

Latest betting odds

We have researched the best MLS odds in America for this game, which are listed here:

• Moneyline: Chicago +335, Nashville -120
• Total Goals: Over/Under 2.5 (-190/+186)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Nashville @ -120 via Novig
• Total Goals: Under 2.5 @ +186 via Novig

According to our MLS best bets, the top play to make on this game is Nashville to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Correct score projections

Here are the top three most likely final scores according to our model, with a 2-1 Nashville win being the most probable:

• Nashville 2-1 Chicago (9.9% probability)
• Nashville 1-1 Chicago (9.6%)
• Nashville 2-0 Chicago (8.8%)

Game info & kickoff details

Saturday's MLS game between Nashville and Chicago in MLS at Geodis Park is scheduled to begin at 9:30 PM ET.

• Who: Nashville SC vs. Chicago Fire
• Date: Saturday, September 19, 2026
• Time: 9:30 PM ET/6:30PM PT
• Venue: Geodis Park

Conclusion

According to our computer model, Nashville has a 59.0% win probability on Saturday, Chicago has a 20.1% win probability, and there is a 20.9% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary MLS prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.