Florida International vs. USF prediction: South Florida favored to win in college football Week 1 [2026]
Dimers' simulation model projects a 77.3% win probability for South Florida at Raymond James Stadium.

South Florida and Florida International will meet in Week 1 college football action at Raymond James Stadium on Saturday, commencing at 7:00 PM ET.
Dimers' advanced college football model projects South Florida as the most likely winner in this Florida International vs. USF prediction.
This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons.
Florida International vs. USF prediction and odds
Our independent predictive model currently gives South Florida a 77.3% chance of defeating Florida International. Our predicted final score has South Florida winning 32-21.
According to our model, Florida International (+14.5) has a 56.2% chance of covering the spread, while the over/under total of 51.5 points has a 54.9% chance of going over.
Latest betting odds
We have sourced the best college football odds in America for this game, which are listed here:
- Spread: Florida International +14.5 (-105) / USF -14.5 (-108)
- Moneyline: Florida International +525, USF -550
- Total: Over/Under 51.5 (-112/-105)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Spread: Florida International +14.5 @ -105 via ESPN BET
- Moneyline: Florida International @ +525 via BetRivers
- Total: Over 51.5 @ -112 via DraftKings
According to our college football best bets, the top play to make on this game is Florida International to win.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & kickoff details
Saturday's college football matchup between USF and Florida International at Raymond James Stadium is scheduled to commence at 7:00 PM ET.
- Who: Florida International vs. South Florida
- Date: Saturday, September 5, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: Raymond James Stadium
College football Week 1 promos
Make the most of Dimers' Florida International vs. South Florida predictions by exploring the Bet365 Sportsbook offer below:
Conclusion
We predict South Florida, with a 77.3% win probability, will likely beat Florida International in Saturday's college football matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.




