Northern Colorado vs. Wyoming prediction: Why Wyoming is favored to win in college football Week 2 [2026]

Using trusted machine learning and data, we have re-simulated the outcome of Northern Colorado vs. Wyoming, forming part of our college football predictions coverage.

Our independent predictive model currently gives Wyoming a 94.9% chance of defeating Northern Colorado. Our predicted final score has Wyoming winning 35-12. According to our model, Northern Colorado (+23.5) has a 52.1% chance of covering the spread, while the 47.5-point over/under has a 51.7% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Northern Colorado +23.5 (-110) / Wyoming -23.5 (+100)
• Moneyline: Northern Colorado +1300, Wyoming -1650
• Total: Over/Under 47.5 (-105/-110)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Northern Colorado +23.5 @ -110 via FanDuel
• Moneyline: Wyoming @ -1650 via DraftKings
• Total: Over 47.5 @ -105 via DraftKings

According to our college football best bets, the top play to make on this game is Wyoming to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between Wyoming and Northern Colorado at Jonah Field at War Memorial Stadium is scheduled to commence at 4:00 PM ET.

• Who: Northern Colorado vs. Wyoming
• Date: Saturday, September 12, 2026
• Time: 4:00 PM ET/1:00PM PT
• Venue: Jonah Field at War Memorial Stadium

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Conclusion

We predict Wyoming, with a 94.9% win probability, will likely beat Northern Colorado in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.