Southern Miss vs. Louisiana-Monroe prediction favors Southern Miss to win in college football Week 9 [2026]

Using innovative machine learning and data, we have re-simulated the result of Southern Miss vs. Louisiana-Monroe, forming part of our college football predictions coverage.

Our independent predictive model currently gives Southern Miss a 61.4% chance of defeating Louisiana-Monroe. Our predicted final score has Southern Miss winning 29-25. According to our model, Southern Miss (-3.5) has a 50.8% chance of covering the spread, while the over/under total of 56.5 points has a 52.7% chance of staying under.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Southern Miss -3.5 (+102) / Louisiana-Monroe +3.5 (-108)
• Moneyline: Southern Miss -153, Louisiana-Monroe +150
• Total: Over/Under 56.5 (+111/-115)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Southern Miss -3.5 @ 50¢ via Novig
• Moneyline: Southern Miss @ 61¢ via Novig
• Total: Over 56.5 @ 48¢ via Novig

According to our college football best bets, the top play to make on this game is Southern Miss -3.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Louisiana-Monroe and Southern Miss at JPS Field at Malone Stadium is scheduled to start at 3:30 PM ET.

• Who: Southern Miss vs. Louisiana-Monroe
• Date: Saturday, October 31, 2026
• Time: 3:30 PM ET/12:30 PM PT
• Venue: JPS Field at Malone Stadium

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Conclusion

We predict Southern Miss, with a 61.4% win probability, will likely beat Louisiana-Monroe in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.