Southern University vs. Alabama State prediction: Why Alabama State is favored to win in college football Week 0 [2026]

Alabama State and Southern University will meet in Week 0 college football action at Legion Field on Saturday, starting at 3:00 PM ET.

Dimers' advanced college football model projects Alabama State as the most likely winner in this Southern University vs. Alabama State prediction.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons..

Southern University vs. Alabama State prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Southern University vs. Alabama State, forming part of our college football predictions coverage.

Our independent predictive model gives Alabama State an 88.2% chance of beating Southern University. Our predicted final score has Alabama State winning 37-18.

According to our model, Southern University (+20) has a 50.9% chance of covering the spread, while the 55-point over/under has a 53.7% chance of going over.

Southern University vs. Alabama State odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Southern University +20 (-110) / Alabama State -20 (-110)
• Moneyline: Southern University +840, Alabama State -1250

All odds are correct at the time of publication and are subject to change.

Southern University vs. Alabama State picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Southern University +20 @ -110 via DraftKings
• Moneyline: Southern University @ +840 via DraftKings
• Total: Over 55 @ -116 via Fanatics

According to our best college football bets, the top play to make on this game is Southern University to win.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Southern University vs. Alabama State game-day updates and essential details

Saturday's college football game between Alabama State and Southern University at Legion Field is scheduled to begin at 3:00 PM ET.

• Who: Southern University vs. Alabama State
• Date: Saturday, August 29, 2026
• Time: 3:00 PM ET/12:00PM PT
• Venue: Legion Field

Conclusion

We predict Alabama State, with an 88.2% win probability, will likely beat Southern University in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.