UAB vs. Louisiana-Lafayette prediction favors Louisiana-Lafayette to win in college football Week 3 [2026]

Using trusted machine learning and statistical analysis, we have re-simulated the outcome of UAB vs. Louisiana-Lafayette, forming part of our college football predictions coverage.

Our leading predictive model currently gives Louisiana-Lafayette a 74.7% chance of defeating UAB. Our predicted final score has Louisiana-Lafayette winning 31-23. According to our model, Louisiana-Lafayette (-7.5) has a 50.8% chance of covering the spread, while the over/under total of 55.5 points has a 50.7% chance of going over.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: UAB +7.5 (-105) / Louisiana-Lafayette -7.5 (-110)
• Moneyline: UAB +280, Louisiana-Lafayette -310
• Total: Over/Under 55.5 (-108/-109)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Louisiana-Lafayette -7.5 @ -110 via DraftKings
• Moneyline: Louisiana-Lafayette @ -310 via bet365
• Total: Over 55.5 @ -108 via DraftKings

According to our college football best bets, the top play to make on this game is Louisiana-Lafayette to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Louisiana-Lafayette and UAB at Cajun Field at Our Lady of Lourdes Stadium is scheduled to commence at 8:00 PM ET.

• Who: UAB vs. Louisiana-Lafayette
• Date: Saturday, September 19, 2026
• Time: 8:00 PM ET/5:00PM PT
• Venue: Cajun Field at Our Lady of Lourdes Stadium

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Conclusion

We predict Louisiana-Lafayette, with a 74.7% win probability, will likely beat UAB in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.