Weber State vs. Colorado prediction: Why Colorado is favored to win in college football Week 2 [2026]

Colorado will square off with Weber State in Week 2 college football action at Folsom Field on Saturday, commencing at 3:30 PM ET.

Dimers' proven college football model projects Colorado as the most likely winner in this Weber State vs. Colorado prediction.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons.

Weber State vs. Colorado prediction and odds

Using trusted machine learning and data analysis, we have re-simulated the outcome of Weber State vs. Colorado, forming part of our college football predictions coverage.

Our famous predictive model gives Colorado a 98.5% chance of defeating Weber State. Our predicted final score has Colorado winning 46-10. According to our model, Weber State (+38.5) has a 55.1% chance of covering the spread, while the over/under total of 57.5 points has a 51.9% chance of staying under.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Weber State +38.5 (-108) / Colorado -38.5 (-105)
• Moneyline: Weber State +2500, Colorado -8000
• Total: Over/Under 57.5 (-110/-108)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Weber State +38.5 @ -108 via DraftKings
• Moneyline: Colorado @ -8000 via DraftKings
• Total: Under 57.5 @ -108 via DraftKings

According to our college football best bets, the top play to make on this game is Weber State +38.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between Colorado and Weber State at Folsom Field is scheduled to commence at 3:30 PM ET.

• Who: Weber State vs. Colorado
• Date: Saturday, September 12, 2026
• Time: 3:30 PM ET/12:30PM PT
• Venue: Folsom Field

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Conclusion

We predict Colorado, with a 98.5% win probability, will likely beat Weber State in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.