Wyoming vs. Central Michigan prediction: Why Wyoming is favored to win in college football Week 3 [2026]

Using innovative machine learning and data analysis, we have re-simulated the result of Wyoming vs. Central Michigan, forming part of our college football predictions coverage.

Our leading predictive model gives Wyoming a 50.6% chance of beating Central Michigan. Our predicted final score has Wyoming winning 21-19. According to our model, the oddsmakers have got it right, and Wyoming and Central Michigan each have a 50% chance of covering the spread, while the over/under total of 38.5 points has a 55.7% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Wyoming -1.5 (-105) / Central Michigan +1.5 (-114)
• Moneyline: Wyoming -112, Central Michigan -105
• Total: Over/Under 38.5 (-109/-110)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Wyoming -1.5 @ -105 via bet365
• Moneyline: Central Michigan @ -105 via bet365
• Total: Over 38.5 @ -109 via BetRivers

According to our college football best bets, the top play to make on this game is Over 38.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between Central Michigan and Wyoming at Kelly/Shorts Stadium is scheduled to begin at 1:00 PM ET.

• Who: Wyoming vs. Central Michigan
• Date: Saturday, September 19, 2026
• Time: 1:00 PM ET/10:00AM PT
• Venue: Kelly/Shorts Stadium

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Conclusion

We predict Wyoming, with a 50.6% win probability, will likely beat Central Michigan in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.