Mississippi vs. Vanderbilt: College Football Week 6 Prediction, Picks & Odds

Mississippi vs. Vanderbilt: Detailed Breakdown

Matchup overview: College Football Week 6

• Teams: Mississippi vs. Vanderbilt
• Date: Saturday, October 10, 2026
• Time: 3:30PM ET
• Venue: FirstBank Stadium

Current betting odds

• Spread: Mississippi (-9.5, -108), Vanderbilt (+9.5, -107)
• Moneyline: Mississippi -350, Vanderbilt +290
• Total (Over/Under): 54.5 points (-110/-105)

Dimers’ win probabilities

• Mississippi: 73.9%
• Vanderbilt: 26.1%

These probabilities come from two machine learning models that assess more than 100 data points for each college football matchup, combining their outputs to project all our major betting markets.

Projected final score

Our predicted final score for this college football matchup is Mississippi 31-23 Vanderbilt.

This prediction draws on each team's scoring trends and player stats, weighed across both of our data models

Our Prediction: Who Wins?

The numbers give the Mississippi a win probability of 73.9%, while the Vanderbilt have a win probability of 26.1%.

Summary

Mississippi faces off against Vanderbilt in college football action at FirstBank Stadium on Saturday, October 10, 2026.

Our Mississippi vs. Vanderbilt predictions, built on real-time data and matchup-specific modeling, help guide your decisions. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert college football predictions and the best college football bets today, while our in-depth analysis includes college football props, college football futures, college football odds, and the latest college football news.