Iowa State vs. Arizona prediction: Why Arizona is favored to win in college football Week 8 [2026]

Using powerful machine learning and data, we have re-simulated the outcome of Iowa State vs. Arizona, forming part of our college football predictions coverage.

Our independent predictive model currently gives Arizona a 78.1% chance of defeating Iowa State. Our predicted final score has Arizona winning 31-20. According to our model, Arizona (-9.5) has a 54.7% chance of covering the spread, while the 51.5-point over/under has a 52.3% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Iowa State +9.5 (+122) / Arizona -9.5 (-125)
• Moneyline: Iowa State +310, Arizona -335
• Total: Over/Under 51.5 (-102/-115)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Iowa State +9.5 @ 45¢ via Novig
• Moneyline: Arizona @ 77¢ via Novig
• Total: Over 51.5 @ -102 via DraftKings

According to our college football best bets, the top play to make on this game is Over 51.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Arizona and Iowa State at Casino Del Sol Stadium is scheduled to start at 7:30 PM ET.

• Who: Iowa State vs. Arizona
• Date: Saturday, October 24, 2026
• Time: 7:30 PM ET/4:30 PM PT
• Venue: Casino Del Sol Stadium

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Conclusion

We predict Arizona, with a 78.1% win probability, will likely beat Iowa State in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.