Diamondbacks vs. Red Sox prediction: Boston favored to win Wednesday's MLB matchup [8/19/2026]
Get Arizona Diamondbacks vs Boston Red Sox predictions for MLB Wednesday.

The Boston Red Sox will take on the Arizona Diamondbacks in MLB action at Fenway Park on Wednesday, beginning at 4:10 PM ET.
Payton Tolle (8-6, 2.97 ERA) will start for the Red Sox, pitting him against Brandon Pfaadt (7-1, 3.11 ERA) for the Diamondbacks.
Dimers' proven MLB model projects the Red Sox as the most likely winner in this Diamondbacks vs. Red Sox prediction.
This article offers a closer look at Wednesday's matchup, including best bets and picks.
Diamondbacks vs. Red Sox prediction: Who will win and cover?
Our leading predictive model currently gives the Red Sox a 56.9% chance of defeating the Diamondbacks.
According to our model, the Diamondbacks (+1.5) have a 60.7% chance of covering the run line, while the over/under total of 8.5 runs has a 58.8% chance of going over,.
Diamondbacks vs. Red Sox odds [8/19/2026]
We have researched the best MLB odds in America for this game, which are listed here:
- Run Line: Diamondbacks +1.5 (-141) / Red Sox -1.5 (+138)
- Moneyline: Diamondbacks +150, Red Sox -148
All odds are correct at the time of publication and are subject to change.
Diamondbacks vs. Red Sox picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Diamondbacks +1.5 @ -141 via DraftKings
- Moneyline: Diamondbacks @ +150 via DraftKings
- Total: Over 8.5 @ +104 via Polymarket
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Diamondbacks vs. Red Sox game-day updates and essential details
Wednesday's MLB action between the Red Sox and Diamondbacks at Fenway Park is scheduled to start at 4:10 PM ET.
- Who: Arizona Diamondbacks vs. Boston Red Sox
- Date: Wednesday, August 19, 2026
- Time: 4:10 PM ET/1:10PM PT
- Venue: Fenway Park
Conclusion
We predict the Red Sox, with a 56.9% win probability, will likely beat the Diamondbacks in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



