Orioles vs. Twins prediction: Why Minnesota is favored to win Wednesday's MLB matchup [8/12/2026]
Get Baltimore Orioles vs Minnesota Twins predictions for MLB Wednesday.

The Minnesota Twins will take on the Baltimore Orioles, in what is expected to be a tight MLB game, at Target Field on Wednesday, beginning at 1:40 PM ET.
The Twins will send Zebby Matthews (5-8, 5.23 ERA) to the mound, up against Shane Baz (4-11, 3.76 ERA) for the Orioles.
Dimers' proven MLB model gives the Twins a slight edge with a 52.7% win probability over the Orioles.
This article offers a closer look at Wednesday's Orioles vs. Twins matchup, including best bets and picks.
Orioles vs. Twins prediction: Who will win and cover?
Our famous predictive model currently gives the Twins a 52.7% chance of beating the Orioles.
According to our model, the Twins (+1.5) have a 63.9% chance of covering the run line, while the over/under total of nine runs has a 55.9% chance of going over,.
Orioles vs. Twins odds [8/12/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Orioles -1.5 (+165) / Twins +1.5 (-170)
- Moneyline: Orioles +100, Twins -104
All odds are correct at the time of publication and are subject to change.
Orioles vs. Twins picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Twins +1.5 @ -170 via DraftKings
- Moneyline: Twins @ -104 via Novig
- Total: Over 9 @ +105 via Bet365
According to our MLB best bets, the top play to make on this game is Over 9 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Orioles vs. Twins game-day updates and essential details
Wednesday's MLB matchup between the Twins and Orioles at Target Field is scheduled to start at 1:40 PM ET.
- Who: Baltimore Orioles vs. Minnesota Twins
- Date: Wednesday, August 12, 2026
- Time: 1:40 PM ET/10:40AM PT
- Venue: Target Field
Conclusion
We predict the Twins, with a 52.7% win probability, will likely beat the Orioles in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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