Cubs vs. Rockies prediction: Why Cubs are favored to win Wednesday's MLB matchup [6/10/2026]

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Written by Dave Garofolo

Get Chicago Cubs vs Colorado Rockies predictions for MLB Wednesday.

Chicago Cubs-Colorado Rockies Predictions and Game Preview.
Chicago Cubs vs. Colorado Rockies MLB prediction for Wednesday, June 10, 2026.

MLB action continues on Wednesday at 8:40 PM ET as the Chicago Cubs square off with the Colorado Rockies at Coors Field.

Michael Lorenzen (2-8, 8.01 ERA) will start on the mound for the Rockies, up against Shota Imanaga (4-6, 4.74 ERA) for the Cubs.

Based on the latest simulations, Dimers' proven MLB model predicts the Cubs as the most likely winner of the Cubs vs. Rockies game.

This article offers a closer look at Wednesday's matchup, including best bets and picks.

Cubs vs. Rockies prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLB matchup between the Cubs and Rockies, forming part of our MLB predictions coverage.

Our independent predictive model gives the Cubs a 59.2% chance of defeating the Rockies.

According to our model, the Rockies (+1.5) have a 50.8% chance of covering the run line, while the over/under total of 12 runs has a 55.0% chance of going over.

 

Cubs vs. Rockies odds [6/10/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Cubs Rockies
Run Line -1.5 (-114) +1.5 (+100)
Moneyline -172 +145
Total o12 (-106) u12 (-112)

All odds are correct at the time of publication and are subject to change.

Cubs vs. Rockies picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Rockies +1.5 +100
Moneyline Rockies +145
Total Over 12 -106

According to our MLB best bets, the top play to make on this game is Over 12 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Cubs vs. Rockies game-day updates and essential details

Wednesday's MLB game between the Rockies and Cubs at Coors Field is scheduled to begin at 8:40 PM ET.

Conclusion

We predict the Cubs, with a 59.2% win probability, will likely beat the Rockies in Wednesday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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