Cubs vs. Brewers prediction: Why Milwaukee is favored to win Tuesday's MLB matchup [9/8/2026]

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Written by Dave Garofolo

Dimers' simulation model projects a 60.4% win probability for the Brewers at American Family Field.

The Chicago Cubs take on the Milwaukee Brewers in MLB action.
Chicago Cubs vs. Milwaukee Brewers MLB prediction for Tuesday, September 8, 2026.

The Milwaukee Brewers will take on the Chicago Cubs in MLB action at American Family Field on Tuesday, commencing at 7:40 PM ET.

Jacob Misiorowski (14-5, 1.97 ERA) will start for the Brewers, up against David Peterson (7-8, 5.39 ERA) for the Cubs.

Dimers' advanced MLB model projects the Brewers as the most likely winner in this Cubs vs. Brewers prediction.

This article offers an expanded analysis of Tuesday's matchup, including best bets and picks.

For more, dive into Jacob Misiorowski's pitching projections.

Cubs vs. Brewers prediction and odds

Using innovative machine learning and data, we have re-simulated the result of Tuesday's MLB game between the Cubs and Brewers, forming part of our MLB predictions coverage.

Our leading predictive model gives the Brewers a 60.4% chance of beating the Cubs.

According to our model, the Cubs (+1.5) have a 56.6% chance of covering the run line, while the over/under total of 7.5 runs has a 52.9% chance of going over.

 

Latest betting odds

We have researched the best MLB odds in America for this game, which are listed here:

  • Run Line: Cubs +1.5 (-111) / Brewers -1.5 (+108)
  • Moneyline: Cubs +194, Brewers -194
  • Total: Over/Under 7.5 (+117/-110)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

  • Run line: Cubs +1.5 @ 53¢ via Novig
  • Moneyline: Cubs @ 34¢ via Novig
  • Total: Over 7.5 @ 46¢ via Polymarket

According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & first pitch details

Tuesday's MLB action between the Brewers and Cubs at American Family Field is scheduled to begin at 7:40 PM ET.

Conclusion

We predict the Brewers, with a 60.4% win probability, will likely beat the Cubs in Tuesday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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