Sep 9, 2026
Cardinals vs. Giants prediction: St. Louis favored to win Wednesday's MLB matchup [9/9/2026]
Read Article Cubs vs. Brewers prediction: Why Milwaukee is favored to win Wednesday's MLB matchup [9/9/2026]
Updated: | First published:
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Written by Dave Garofolo, Content Producer
Dimers' simulation model projects a 53.8% win probability for the Brewers at American Family Field.
The Milwaukee Brewers will take on the Chicago Cubs, in what is expected to be a tight MLB game, at American Family Field on Wednesday, beginning at 7:40 PM ET.
The Brewers will send Logan Henderson (9-3, 2.48 ERA) to the mound, pitting him against Kevin Gausman (9-11, 4.38 ERA) for the Cubs.
Dimers' advanced MLB model gives the Brewers a slight edge with a 53.8% win probability over the Cubs.
This article offers a complete Cubs vs. Brewers prediction, including best bets and picks.
Cubs vs. Brewers prediction and odds
Using innovative machine learning and data, we have re-simulated the result of Wednesday's MLB game between the Cubs and Brewers, forming part of our MLB predictions coverage.
Our independent predictive model currently gives the Brewers a 53.8% chance of defeating the Cubs.
According to our model, the Cubs (+1.5) have a 63.1% chance of covering the run line, while the 7.5-run over/under has a 54.9% chance of going over.
Latest betting odds
We have researched the best MLB odds in America for this game, which are listed here:
- Run Line: Cubs +1.5 (-174) / Brewers -1.5 (+170)
- Moneyline: Cubs +120, Brewers -122
- Total: Over/Under 7.5 (-104/+101)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Brewers -1.5 @ 37¢ via Polymarket
- Moneyline: Cubs @ 45¢ via Novig
- Total: Over 7.5 @ 51¢ via Novig
According to our best MLB bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & first pitch details
Wednesday's MLB matchup between the Brewers and Cubs at American Family Field is scheduled to start at 7:40 PM ET.
- Who: Chicago Cubs vs. Milwaukee Brewers
- Date: Wednesday, September 9, 2026
- Time: 7:40 PM ET/4:40PM PT
- Venue: American Family Field
Conclusion
We predict the Brewers, with a 53.8% win probability, will likely beat the Cubs in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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