Aug 22, 2026
Twins vs. Padres prediction: San Diego favored to win Saturday's MLB matchup [8/22/2026]
Read Article Cubs vs. Mariners prediction: Seattle favored to win Saturday's MLB matchup [8/22/2026]
Updated: | First published:
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Written by Jason Bevilacqua, Head of Content and Communities
Get Chicago Cubs vs Seattle Mariners predictions for MLB Saturday.
The Seattle Mariners will square off with the Chicago Cubs, in what is expected to be a close MLB game, at T-Mobile Park on Saturday, beginning at 7:15 PM ET.
Kade Anderson (0-0, 0.00 ERA) will start on the mound for the Mariners, up against David Peterson (7-7, 5.29 ERA) for the Cubs.
Dimers' proven MLB model gives the Mariners a slight edge with a 53.1% win probability over the Cubs.
This article offers a complete Cubs vs. Mariners prediction, including best bets and picks.
Cubs vs. Mariners prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the result of Saturday's MLB game between the Cubs and Mariners, forming part of our MLB predictions coverage.
Our leading predictive model gives the Mariners a 53.1% chance of defeating the Cubs.
According to our model, the Cubs (+1.5) have a 64.5% chance of covering the run line, while the 7.5-run over/under has a 51.5% chance of going over.
Cubs vs. Mariners odds [8/22/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Cubs +1.5 (-220) / Mariners -1.5 (+180)
- Moneyline: Cubs +108, Mariners -108
All odds are correct at the time of publication and are subject to change.
Cubs vs. Mariners picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Mariners -1.5 @ +180 via DraftKings
- Moneyline: Mariners @ -108 via Polymarket
- Total: Over 7.5 @ +106 via Novig
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Cubs vs. Mariners game-day updates and essential details
Saturday's MLB matchup between the Mariners and Cubs at T-Mobile Park is scheduled to begin at 7:15 PM ET.
- Who: Chicago Cubs vs. Seattle Mariners
- Date: Saturday, August 22, 2026
- Time: 7:15 PM ET/4:15PM PT
- Venue: T-Mobile Park
Conclusion
We predict the Mariners, with a 53.1% win probability, will likely beat the Cubs in Saturday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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