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Read Article Cubs vs. Cardinals prediction: Cubs favored to win Sunday's MLB matchup [5/31/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Chicago Cubs vs St. Louis Cardinals predictions for MLB Sunday.
MLB action continues on Sunday at 7:20 PM ET as the Chicago Cubs take on the St. Louis Cardinals at Busch Stadium.
Matthew Liberatore (2-3, 4.76 ERA) will get the ball for the Cardinals, up against Jordan Wicks (0-1, 16.62 ERA) for the Cubs.
Based on the latest simulations, Dimers' advanced MLB model gives the Cubs a slight edge with a 51% win probability over the Cardinals.
This article offers further insights into Sunday's Cubs vs. Cardinals matchup, including best bets and picks.
Cubs vs. Cardinals prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the result of Sunday's MLB game between the Cubs and Cardinals, forming part of our MLB predictions coverage.
Our famous predictive model currently gives the Cubs a 51% chance of defeating the Cardinals.
According to our model, the Cubs (+1.5) have a 68% chance of covering the run line, while the over/under total of 8.5 runs has a 51% chance of going over.
Cubs vs. Cardinals odds [5/31/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Cubs | Cardinals |
|---|---|---|
| Run Line | +1.5 (-220) | -1.5 (+165) |
| Moneyline | +102 | -120 |
| Total | o8.5 (-112) | u8.5 (-104) |
All odds are correct at the time of publication and are subject to change.
Cubs vs. Cardinals picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Cubs +1.5 | -220 |
| Moneyline | Cubs | +102 |
| Total | Over 8.5 | -112 |
According to our MLB best bets, the top play to make on this game is Cubs to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Cubs vs. Cardinals game-day updates and essential details
Sunday's MLB matchup between the Cardinals and Cubs at Busch Stadium is scheduled to start at 7:20 PM ET.
- Who: Chicago Cubs vs. St. Louis Cardinals
- Date: Sunday, May 31, 2026
- Time: 7:20 PM ET/4:20PM PT
- Venue: Busch Stadium
Conclusion
We predict the Cubs, with a 51% win probability, will likely beat the Cardinals in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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