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Read Article White Sox vs. Twins prediction: Why Minnesota is favored to win Friday's MLB matchup [8/28/2026]
Updated: | First published:
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Written by Jason Bevilacqua, Head of Content and Communities
Get Chicago White Sox vs Minnesota Twins predictions for MLB Friday.
The Minnesota Twins will face the Chicago White Sox in MLB action at Target Field on Friday, commencing at 8:10 PM ET.
The Twins will send Dean Kremer (2-4, 5.22 ERA) to the mound, up against Luis Castillo (4-10, 5.19 ERA) for the White Sox.
Dimers' advanced MLB model projects the Twins as the most likely winner in this White Sox vs. Twins prediction.
This article offers an expanded analysis of Friday's matchup, including best bets and picks.
White Sox vs. Twins prediction: Who will win and cover?
Using trusted machine learning and data analysis, we have simulated the outcome of Friday's MLB matchup between the White Sox and Twins, forming part of our MLB predictions coverage.
Our famous predictive model currently gives the Twins a 55.3% chance of defeating the White Sox.
According to our model, the White Sox (+1.5) have a 61.5% chance of covering the run line, while the over/under total of 8.5 runs has a 58.1% chance of going over.
White Sox vs. Twins odds [8/28/2026]
We have researched the best MLB odds in America for this game, which are listed here:
- Run Line: White Sox +1.5 (-175) / Twins -1.5 (+178)
- Moneyline: White Sox +120, Twins -122
All odds are correct at the time of publication and are subject to change.
White Sox vs. Twins picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Twins -1.5 @ +178 via DraftKings
- Moneyline: Twins @ -122 via Novig
- Total: Over 8.5 @ -113 via Polymarket
According to our best MLB bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
White Sox vs. Twins game-day updates and essential details
Friday's MLB game between the Twins and White Sox at Target Field is scheduled to commence at 8:10 PM ET.
- Who: Chicago White Sox vs. Minnesota Twins
- Date: Friday, August 28, 2026
- Time: 8:10 PM ET/5:10PM PT
- Venue: Target Field
Conclusion
We predict the Twins, with a 55.3% win probability, will likely beat the White Sox in Friday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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