Reds vs. Cardinals prediction: St. Louis favored to win Friday's MLB matchup [7/24/2026]
Get Cincinnati Reds vs St. Louis Cardinals predictions for MLB Friday.
The St. Louis Cardinals and Cincinnati Reds will meet in MLB action at Busch Stadium on Friday, starting at 8:15 PM ET.
The Cardinals will start Dustin May (5-7, 4.78 ERA), while the Reds have opted for Rhett Lowder (3-7, 5.75 ERA).
Based on the latest simulations, Dimers' proven MLB model predicts the Cardinals as the most likely winner of the Reds vs. Cardinals game.
This article offers a closer look at Friday's matchup, including best bets and picks.
Reds vs. Cardinals prediction: Who will win and cover?
Our famous predictive model gives the Cardinals a 56.9% chance of beating the Reds.
According to our model, the Reds (+1.5) have a 60.1% chance of covering the run line, while the 8.5-run over/under has a 50.6% chance of going over,.
Reds vs. Cardinals odds [7/24/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Reds | Cardinals |
|---|---|---|
| Run Line | +1.5 (-144) | -1.5 (+150) |
| Moneyline | +150 | -144 |
| Total | o8.5 (+111) | u8.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Reds vs. Cardinals picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Reds +1.5 | -144 |
| Moneyline | Reds | +150 |
| Total | Over 8.5 | +111 |
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Reds vs. Cardinals game-day updates and essential details
Friday's MLB game between the Cardinals and Reds at Busch Stadium is scheduled to start at 8:15 PM ET.
- Who: Cincinnati Reds vs. St. Louis Cardinals
- Date: Friday, July 24, 2026
- Time: 8:15 PM ET/5:15PM PT
- Venue: Busch Stadium
Conclusion
We predict the Cardinals, with a 56.9% win probability, will likely beat the Reds in Friday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Continue reading with Dimers Pro
Join now to unlock this article and get full access to our predictions and betting tools. Cancel anytime.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
