Jul 22, 2026
Tigers vs. Cubs prediction: Why Cubs are favored to win Wednesday's MLB matchup [7/22/2026]
Read Article Guardians vs. Brewers prediction: Why Milwaukee is favored to win Thursday's MLB matchup [6/18/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Cleveland Guardians vs Milwaukee Brewers predictions for MLB Thursday.
The Milwaukee Brewers will face the Cleveland Guardians in MLB action at American Family Field on Thursday, starting at 2:10 PM ET.
The Brewers will have Shane Drohan (3-2, 3.59 ERA) as their starting pitcher, while the Guardians have opted for Parker Messick (6-3, 2.68 ERA).
Based on the latest simulation results, Dimers' proven MLB model predicts the Brewers as the most likely winner of the Guardians vs. Brewers game.
This article offers an expanded analysis of Thursday's matchup, including best bets and picks.
Guardians vs. Brewers prediction: Who will win and cover?
Using powerful machine learning and data analysis, we have simulated the outcome of Thursday's MLB game between the Guardians and Brewers, forming part of our MLB predictions coverage.
Our leading predictive model gives the Brewers a 56.3% chance of defeating the Guardians.
According to our model, the Guardians (+1.5) have a 62.4% chance of covering the run line, while the 7.5-run over/under has a 54.1% chance of going over,.
Guardians vs. Brewers odds [6/18/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Guardians | Brewers |
|---|---|---|
| Run Line | +1.5 (-184) | -1.5 (+155) |
| Moneyline | +124 | -145 |
| Total | o7.5 (-102) | u7.5 (-114) |
All odds are correct at the time of publication and are subject to change.
Guardians vs. Brewers picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Brewers -1.5 | +155 |
| Moneyline | Guardians | +124 |
| Total | Over 7.5 | -102 |
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Guardians vs. Brewers game-day updates and essential details
Thursday's MLB matchup between the Brewers and Guardians at American Family Field is scheduled to commence at 2:10 PM ET.
- Who: Cleveland Guardians vs. Milwaukee Brewers
- Date: Thursday, June 18, 2026
- Time: 2:10 PM ET/11:10AM PT
- Venue: American Family Field
Conclusion
We predict the Brewers, with a 56.3% win probability, will likely beat the Guardians in Thursday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
Advertiser disclosure
