Astros vs. White Sox prediction: Why Houston is favored to win Sunday's MLB matchup [7/26/2026]
Get Houston Astros vs Chicago White Sox predictions for MLB Sunday.
The Chicago White Sox and Houston Astros will meet in MLB action at Rate Field on Sunday, starting at 2:10 PM ET.
The White Sox will send Erick Fedde (5-6, 4.16 ERA) to the mound, while the Astros have opted for Ronel Blanco (0-0, 7.71 ERA).
Based on updated simulation results, Dimers' proven MLB model gives the Astros a slight edge with a 53.3% win probability over the White Sox.
This article offers a closer look at Sunday's Astros vs. White Sox matchup, including best bets and picks.
Astros vs. White Sox prediction: Who will win and cover?
Our famous predictive model currently gives the Astros a 53.3% chance of defeating the White Sox.
According to our model, the Astros (+1.5) have a 68.1% chance of covering the run line, while the 9.5-run over/under has an equal 50-50 chance of hitting,.
Astros vs. White Sox odds [7/26/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Astros | White Sox |
|---|---|---|
| Run Line | +1.5 (-220) | -1.5 (+180) |
| Moneyline | +102 | -104 |
| Total | o9.5 (+108) | u9.5 (-113) |
All odds are correct at the time of publication and are subject to change.
Astros vs. White Sox picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Astros +1.5 | -220 |
| Moneyline | Astros | +102 |
| Total | Over 9.5 | +108 |
According to our MLB best bets, the top play to make on this game is Astros to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Astros vs. White Sox game-day updates and essential details
Sunday's MLB game between the White Sox and Astros at Rate Field is scheduled to start at 2:10 PM ET.
- Who: Houston Astros vs. Chicago White Sox
- Date: Sunday, July 26, 2026
- Time: 2:10 PM ET/11:10AM PT
- Venue: Rate Field
Conclusion
We predict the Astros, with a 53.3% win probability, will likely beat the White Sox in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
