Astros vs. Yankees prediction: Yankees favored to win Wednesday's MLB matchup [8/26/2026]
Get Houston Astros vs New York Yankees predictions for MLB Wednesday.

The New York Yankees and Houston Astros will lock horns in MLB action at Yankee Stadium on Wednesday, starting at 7:05 PM ET.
Elmer Rodríguez (0-2, 4.76 ERA) will be the starting pitcher for the Yankees, while the Astros have opted for Peter Lambert (8-7, 3.68 ERA).
Dimers' proven MLB model gives the Yankees a slight edge with a 51.9% win probability over the Astros.
This article offers a complete Astros vs. Yankees prediction, including best bets and picks.
Astros vs. Yankees prediction: Who will win and cover?
Our leading predictive model gives the Yankees a 51.9% chance of beating the Astros.
According to our model, the Astros (+1.5) have a 64.1% chance of covering the run line, while the over/under total of 8.5 runs has a 57.4% chance of going over.
Astros vs. Yankees odds [8/26/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Astros +1.5 (-186) / Yankees -1.5 (+170)
- Moneyline: Astros +113, Yankees -117
All odds are correct at the time of publication and are subject to change.
Astros vs. Yankees picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Astros +1.5 @ -186 via DraftKings
- Moneyline: Astros @ +113 via Polymarket
- Total: Over 8.5 @ -115 via Novig
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Astros vs. Yankees game-day updates and essential details
Wednesday's MLB game between the Yankees and Astros at Yankee Stadium is scheduled to start at 7:05 PM ET.
- Who: Houston Astros vs. New York Yankees
- Date: Wednesday, August 26, 2026
- Time: 7:05 PM ET/4:05PM PT
- Venue: Yankee Stadium
Conclusion
We predict the Yankees, with a 51.9% win probability, will likely beat the Astros in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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