Astros vs. Yankees prediction: Yankees favored to win Thursday's MLB matchup [8/27/2026]
Get Houston Astros vs New York Yankees predictions for MLB Thursday.

The New York Yankees will square off with the Houston Astros in MLB action at Yankee Stadium on Thursday, beginning at 7:05 PM ET.
The Yankees will have Gerrit Cole (7-6, 3.11 ERA) as their starting pitcher, while the Astros are going with Hayden Wesneski (3-1, 4.23 ERA).
Dimers' advanced MLB model projects the Yankees as the most likely winner in this Astros vs. Yankees prediction.
This article offers a closer look at Thursday's matchup, including best bets and picks.
Astros vs. Yankees prediction: Who will win and cover?
Our independent predictive model gives the Yankees a 56.2% chance of beating the Astros.
According to our model, the Astros (+1.5) have a 60.9% chance of covering the run line, while the 8.5-run over/under has a 52.1% chance of going over.
Astros vs. Yankees odds [8/27/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Astros +1.5 (-138) / Yankees -1.5 (+135)
- Moneyline: Astros +153, Yankees -149
All odds are correct at the time of publication and are subject to change.
Astros vs. Yankees picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Astros +1.5 @ -138 via DraftKings
- Moneyline: Astros @ +153 via Novig
- Total: Over 8.5 @ +117 via Polymarket
According to our best MLB bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Astros vs. Yankees game-day updates and essential details
Thursday's MLB game between the Yankees and Astros at Yankee Stadium is scheduled to commence at 7:05 PM ET.
- Who: Houston Astros vs. New York Yankees
- Date: Thursday, August 27, 2026
- Time: 7:05 PM ET/4:05PM PT
- Venue: Yankee Stadium
Conclusion
We predict the Yankees, with a 56.2% win probability, will likely beat the Astros in Thursday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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