Angels vs. Astros prediction: Houston favored to win Thursday's MLB matchup [8/20/2026]
Get Los Angeles Angels vs Houston Astros predictions for MLB Thursday.

The Houston Astros will square off with the Los Angeles Angels in MLB action at Daikin Park on Thursday, beginning at 8:10 PM ET.
Peter Lambert (8-6, 3.11 ERA) will be the starting pitcher for the Astros, while the Angels have opted for Grayson Rodriguez (3-5, 7.17 ERA).
Dimers' advanced MLB model projects the Astros as the most likely winner in this Angels vs. Astros prediction.
This article offers a closer look at Thursday's matchup, including best bets and picks.
Angels vs. Astros prediction: Who will win and cover?
Our famous predictive model gives the Astros a 63.9% chance of defeating the Angels.
According to our model, the Angels (+1.5) have a 53.7% chance of covering the run line, while the 8.5-run over/under has a 52.6% chance of going over,.
Angels vs. Astros odds [8/20/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Angels +1.5 (-122) / Astros -1.5 (+122)
- Moneyline: Angels +170, Astros -178
All odds are correct at the time of publication and are subject to change.
Angels vs. Astros picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Astros -1.5 @ +122 via DraftKings
- Moneyline: Astros @ -178 via Bet365
- Total: Over 8.5 @ +117 via Polymarket
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Angels vs. Astros game-day updates and essential details
Thursday's MLB action between the Astros and Angels at Daikin Park is scheduled to start at 8:10 PM ET.
- Who: Los Angeles Angels vs. Houston Astros
- Date: Thursday, August 20, 2026
- Time: 8:10 PM ET/5:10PM PT
- Venue: Daikin Park
Conclusion
We predict the Astros, with a 63.9% win probability, will likely beat the Angels in Thursday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.


