Dodgers vs. Phillies prediction: Why Dodgers are favored to win Wednesday's MLB matchup [7/22/2026]
Get Los Angeles Dodgers vs Philadelphia Phillies predictions for MLB Wednesday.

The Philadelphia Phillies will square off with the Los Angeles Dodgers, in what is expected to be a tight MLB game, at Citizens Bank Park on Wednesday, beginning at 6:40 PM ET.
Aaron Nola (3-7, 5.68 ERA) will start on the mound for the Phillies, while the Dodgers are going with Eric Lauer (4-5, 4.81 ERA).
Based on the latest simulations, Dimers' advanced MLB model gives the Dodgers a slight edge with a 54.0% win probability over the Phillies.
This article offers a closer look at Wednesday's Dodgers vs. Phillies matchup, including best bets and picks.
Dodgers vs. Phillies prediction: Who will win and cover?
Our leading predictive model gives the Dodgers a 54.0% chance of defeating the Phillies.
According to our model, the Phillies (+1.5) have a 56.6% chance of covering the run line, while the 9.5-run over/under has a 51.3% chance of going over,.
Dodgers vs. Phillies odds [7/22/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Dodgers | Phillies |
|---|---|---|
| Run Line | -1.5 (+138) | +1.5 (-144) |
| Moneyline | -108 | +106 |
| Total | o9.5 (+104) | u9.5 (-106) |
All odds are correct at the time of publication and are subject to change.
Dodgers vs. Phillies picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Dodgers -1.5 | +138 |
| Moneyline | Dodgers | -108 |
| Total | Over 9.5 | +104 |
According to our MLB best bets, the top play to make on this game is Over 9.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Dodgers vs. Phillies game-day updates and essential details
Wednesday's MLB game between the Phillies and Dodgers at Citizens Bank Park is scheduled to begin at 6:40 PM ET.
- Who: Los Angeles Dodgers vs. Philadelphia Phillies
- Date: Wednesday, July 22, 2026
- Time: 6:40 PM ET/3:40PM PT
- Venue: Citizens Bank Park
Conclusion
We predict the Dodgers, with a 54.0% win probability, will likely beat the Phillies in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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