Sep 2, 2026
Giants vs. Pirates prediction: Why Pittsburgh is favored to win Wednesday's MLB matchup [9/2/2026]
Read Article Brewers vs. Cubs prediction: Why Milwaukee is favored to win Wednesday's MLB matchup [9/2/2026]
Updated: | First published:
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Written by Dave Garofolo, Content Producer
Dimers' simulation model projects a 52.8% win probability for the Brewers at Wrigley Field.
The Chicago Cubs will face the Milwaukee Brewers, in what is expected to be a tight MLB game, at Wrigley Field on Wednesday, beginning at 7:40 PM ET.
David Peterson (7-7, 5.11 ERA) will be on the bump for the Cubs, up against Jacob Misiorowski (14-5, 1.73 ERA) for the Brewers.
Dimers' proven MLB model gives the Brewers a slight edge with a 52.8% win probability over the Cubs.
This article offers a complete Brewers vs. Cubs prediction, including best bets and picks.
For more, dive into Jacob Misiorowski's projected pitching stats.
Brewers vs. Cubs prediction and odds
Using innovative machine learning and data, we have simulated the result of Wednesday's MLB game between the Brewers and Cubs, forming part of our MLB predictions coverage.
Our independent predictive model gives the Brewers a 52.8% chance of beating the Cubs.
According to our model, the Cubs (+1.5) have a 58.9% chance of covering the run line, while the 8.5-run over/under has a 55.8% chance of going over.
Latest betting odds
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Brewers -1.5 (+117) / Cubs +1.5 (-120)
- Moneyline: Brewers -138, Cubs +135
- Total: Over/Under 8.5 (+100/+108)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Cubs +1.5 @ -120 via bet365
- Moneyline: Cubs @ +135 via bet365
- Total: Over 8.5 @ +100 via bet365
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & first pitch details
Wednesday's MLB action between the Cubs and Brewers at Wrigley Field is scheduled to start at 7:40 PM ET.
- Who: Milwaukee Brewers vs. Chicago Cubs
- Date: Wednesday, September 2, 2026
- Time: 7:40 PM ET/4:40PM PT
- Venue: Wrigley Field
Conclusion
We predict the Brewers, with a 52.8% win probability, will likely beat the Cubs in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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