Brewers vs. Padres prediction: San Diego favored to win Monday's MLB matchup [8/10/2026]

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Written by Dave Garofolo

Get Milwaukee Brewers vs San Diego Padres predictions for MLB Monday.

Milwaukee Brewers-San Diego Padres Predictions and Game Preview.
Milwaukee Brewers vs. San Diego Padres MLB prediction for Monday, August 10, 2026.

The San Diego Padres will square off with the Milwaukee Brewers, in what is expected to be a tight MLB game, at Petco Park on Monday, starting at 9:40 PM ET.

The Padres will have Casey Mize (4-7, 3.40 ERA) as their starting pitcher, up against Logan Henderson (6-1, 2.70 ERA) for the Brewers.

Dimers' proven MLB model gives the Padres a slight edge with a 50.7% win probability over the Brewers.

This article offers further insights into Monday's Brewers vs. Padres matchup, including best bets and picks.

Brewers vs. Padres prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Monday's MLB matchup between the Brewers and Padres, forming part of our MLB predictions coverage.

Our famous predictive model gives the Padres a 50.7% chance of beating the Brewers.

According to our model, the Padres (+1.5) have a 64.1% chance of covering the run line, while the 7.5-run over/under has a 50.4% chance of going over,.

 

Brewers vs. Padres odds [8/10/2026]

We have researched the best MLB odds in America for this game, which are listed here:

  • Run Line: Brewers -1.5 (+156) / Padres +1.5 (-163)
  • Moneyline: Brewers -113, Padres +111

All odds are correct at the time of publication and are subject to change.

Brewers vs. Padres picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

  • Run line: Padres +1.5 @ -163 via DraftKings
  • Moneyline: Padres @ +111 via Novig
  • Total: Over 7.5 @ +122 via Novig

According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Brewers vs. Padres game-day updates and essential details

Monday's MLB game between the Padres and Brewers at Petco Park is scheduled to begin at 9:40 PM ET.

Conclusion

We predict the Padres, with a 50.7% win probability, will likely beat the Brewers in Monday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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