Jul 22, 2026
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Read Article Twins vs. Cubs prediction: Why Cubs are favored to win Saturday's MLB matchup [7/18/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Minnesota Twins vs Chicago Cubs predictions for MLB Saturday.
The Chicago Cubs will square off with the Minnesota Twins in MLB action at Wrigley Field on Saturday, starting at 2:20 PM ET.
Matthew Boyd (5-1, 4.50 ERA) will start on the mound for the Cubs, pitting him against Taj Bradley (9-3, 3.59 ERA) for the Twins.
Based on updated simulations, Dimers' proven MLB model predicts the Cubs as the most likely winner of the Twins vs. Cubs game.
This article offers an expanded analysis of Saturday's matchup, including best bets and picks.
Twins vs. Cubs prediction: Who will win and cover?
Using trusted machine learning and data analysis, we have simulated the outcome of Saturday's MLB matchup between the Twins and Cubs, forming part of our MLB predictions coverage.
Our leading predictive model gives the Cubs a 56.9% chance of beating the Twins.
According to our model, the Twins (+1.5) have a 60.1% chance of covering the run line, while the over/under total of 8.5 runs has a 55.4% chance of going over,.
Twins vs. Cubs odds [7/18/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Twins | Cubs |
|---|---|---|
| Run Line | +1.5 (-150) | -1.5 (+147) |
| Moneyline | +141 | -144 |
| Total | o8.5 (+108) | u8.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Twins vs. Cubs picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Twins +1.5 | -150 |
| Moneyline | Twins | +141 |
| Total | Over 8.5 | +108 |
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Twins vs. Cubs game-day updates and essential details
Saturday's MLB action between the Cubs and Twins at Wrigley Field is scheduled to start at 2:20 PM ET.
- Who: Minnesota Twins vs. Chicago Cubs
- Date: Saturday, July 18, 2026
- Time: 2:20 PM ET/11:20AM PT
- Venue: Wrigley Field
Conclusion
We predict the Cubs, with a 56.9% win probability, will likely beat the Twins in Saturday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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