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Read Article MLB picks today: Friday's MLB best bets include Blue Jays vs. Orioles play [5/29/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get MLB picks today and best bets for Friday, May 29, 2026.
Today’s MLB picks for May 29, 2026 are here, with Blue Jays vs. Orioles and Royals vs. Rangers among the top plays identified by our model across Friday’s MLB play.
Dimers’ predictive analytics engine runs 24/7, searching the latest baseball odds to find real betting edges. The result? Data-backed plays that help Dimers Pro members make smarter decisions.
List of MLB best bets today [5/29, updated 10:07PM ET]
Below, you’ll find today’s top 10 baseball bets, ranked by edge for Friday, May 29, 2026.
Blue Jays vs. Orioles over 7.5 runs (+100)
- Edge: 7.6%
- Probability: 57.6%
- Matchup: Blue Jays vs. Orioles (4:05PM ET, Saturday)
Our model has identified value on over 7.5 runs in Blue Jays vs. Orioles at +100 odds. A 57.6% probability produces an edge of 7.6%, making this the strongest play for today's MLB slate.
Royals vs. Rangers over 7.5 runs (-113)
- Edge: 7.0%
- Probability: 60%
- Matchup: Royals vs. Rangers (4:05PM ET, Saturday)
Royals vs. Rangers over 7.5 runs carries a 7.0% edge and a probability of 60% at -113 odds, according to our model.
Red Sox vs. Guardians over 7.5 runs (+130)
- Edge: 6.7%
- Probability: 50.2%
- Matchup: Red Sox vs. Guardians (4:10PM ET, Saturday)
Red Sox vs. Guardians over 7.5 runs at +130 odds shows a 6.7% edge, supported by a 50.2% probability in simulations.
Padres vs. Nationals over 7.5 runs (+100)
- Edge: 4.9%
- Probability: 54.9%
- Matchup: Padres vs. Nationals (4:05PM ET, Saturday)
A 4.9% edge and 54.9% probability make Padres vs. Nationals over 7.5 runs at a value play in the Padres vs. Nationals matchup, per our model.
Twins vs. Pirates over 8.5 runs (+111)
- Edge: 4.6%
- Probability: 52.1%
- Matchup: Twins vs. Pirates (4:05PM ET, Saturday)
Twins vs. Pirates over 8.5 runs at +111 odds presents a 4.6% edge, with simulations resulting in a probability of 52.1%.
Braves vs. Reds over 9.5 runs (+106)
- Edge: 4.4%
- Probability: 52.9%
- Matchup: Braves vs. Reds (7:15PM ET, Saturday)
Our model finds value on over 9.5 runs in Braves vs. Reds at +106 odds, supported by an edge of 4.4%.
Mets -1.5 (+178)
- Edge: 4.3%
- Probability: 40.3%
- Matchup: Marlins vs. Mets (4:10PM ET, Saturday)
Our model has uncovered value on Mets -1.5 at +178 odds. A 40.3% probability produces a 4.3% edge, making this a strong play for today's MLB action.
Angels vs. Rays over 7.5 runs (+125)
- Edge: 4.3%
- Probability: 48.8%
- Matchup: Angels vs. Rays (4:10PM ET, Saturday)
A 4.3% edge on a 48.8% probability makes over 7.5 runs at +125 odds a solid value play in today's Angels vs. Rays matchup.
Athletics ML (+141)
- Edge: 3.8%
- Probability: 45.3%
- Matchup: Yankees vs. Athletics (10:05PM ET, Saturday)
Our model projects value on Athletics to win at +141 odds. A 45.3% probability produces a 3.8% edge, making Athletics the favorable ML play in today's matchup.
Brewers vs. Astros over 8.5 runs (-106)
- Edge: 3.5%
- Probability: 55%
- Matchup: Brewers vs. Astros (4:10PM ET, Saturday)
Rounding out our top 10 bets, Brewers vs. Astros over 8.5 runs at -106 odds shows a 55% probability and a 3.5% edge.
MLB best bets summary: Friday, 5/29/2026
As of 10:07PM ET, here are our top MLB bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Probability |
|---|---|---|---|---|
| Blue Jays vs. Orioles | Over 7.5 Runs | +100 @ Polymarket | 7.6% | 57.6% |
| Royals vs. Rangers | Over 7.5 Runs | -113 @ Polymarket | 7.0% | 60% |
| Red Sox vs. Guardians | Over 7.5 Runs | +130 @ Polymarket | 6.7% | 50.2% |
| Padres vs. Nationals | Over 7.5 Runs | +100 @ Polymarket | 4.9% | 54.9% |
| Twins vs. Pirates | Over 8.5 Runs | +111 @ Kalshi | 4.6% | 52.1% |
| Braves vs. Reds | Over 9.5 Runs | +106 @ Kalshi | 4.4% | 52.9% |
| Marlins vs. Mets | Mets -1.5 | +178 @ Kalshi | 4.3% | 40.3% |
| Angels vs. Rays | Over 7.5 Runs | +125 @ Kalshi | 4.3% | 48.8% |
| Yankees vs. Athletics | Athletics ML | +141 @ Kalshi | 3.8% | 45.3% |
| Brewers vs. Astros | Over 8.5 Runs | -106 @ Kalshi | 3.5% | 55% |
List of upcoming MLB games to bet on [5/29/2026]
- D-Backs vs. Mariners (10:10PM ET, Friday)
- Phillies vs. Dodgers (10:15PM ET, Friday)
- Tigers vs. White Sox (2:10PM ET, Saturday)
- Twins vs. Pirates (4:05PM ET, Saturday)
- Blue Jays vs. Orioles (4:05PM ET, Saturday)
- Royals vs. Rangers (4:05PM ET, Saturday)
- Padres vs. Nationals (4:05PM ET, Saturday)
- Angels vs. Rays (4:10PM ET, Saturday)
- Red Sox vs. Guardians (4:10PM ET, Saturday)
- Marlins vs. Mets (4:10PM ET, Saturday)
- Brewers vs. Astros (4:10PM ET, Saturday)
- Braves vs. Reds (7:15PM ET, Saturday)
- Cubs vs. Cardinals (7:15PM ET, Saturday)
- Yankees vs. Athletics (10:05PM ET, Saturday)
Conclusion
Our MLB best bets are locked and loaded for May 29, 2026, featuring plays such as over 7.5 runs in the Blue Jays vs. Orioles matchup and over 7.5 runs in the Royals vs. Rangers matchup. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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